Some people may think that moving to another area may give them better job and business opportunities. If you think likewise, you should think about it first. You have to think of your trade offs or the things that you have to give up. There are some instances that after a person moved, he may find it hard to find another job or if he will find one, it will decrease the time that he can spend with his family. Also, when you move to a place that is very far from your family yet you can't bear not to see them often, staying may save you a lot of money that is spent on travel expenses.
 
You also have to think of the living cost that you have to maintain when you move out. Isolating yourself in a place where the lifestyle is simple and cheap but far from basic services like hospitals and schools for the kids, you may be wasting a lot of money. Also, you do not really know if things will work out the way that you expect. If you are not yet financially and emotionally ready for this big risk, you may consider staying for a few years or so.